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Finasteride is a hair loss treatment approved by the FDA (U.S. Food and Drug Administration) to treat androgenic alopecia in men (male pattern hair loss) and benign prostatic hyperplasia (BHP, or ...
Then came finasteride, a medication for treating hair loss that gained approval from the Federal Drug Administration (FDA) in 1997 as brand-name Propecia®. How Long Do Finasteride Results for ...
The results of these clinical trials: After using finasteride for 10 years, 99.1 percent of the men displayed a prevention of hair loss progression, with 91.5 percent also showing improvements in ...
Finasteride is most effective on the crown but can reduce hair loss in all areas of the scalp. [27] [28] Finasteride has also been tested for pattern hair loss in women; however, the results were no better than placebo. [29] Finasteride is less effective in the treatment of scalp hair loss than dutasteride. [30] [31]
Finasteride (brand names Proscar, Propecia) inhibits the function of two of the isoenzymes (types 2 and 3) of 5α-reductase. [ 6 ] [ 7 ] It decreases circulating DHT levels by up to about 70%. [ 8 ] Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%.
Finasteride potently inhibits 5α-R2 at a mean inhibitory concentration IC 50 of 69 nM, but is less effective with 5α-R1 with an IC 50 of 360 nM. [21] Finasteride decreases mean serum level of DHT by 71% after 6 months, [22] and was shown in vitro to inhibit 5α-R3 at a similar potency to 5α-R2 in transfected cell lines. [2]
Let’s talk 5mg finasteride vs 1mg—two different doses, one powerful hair loss treatment. Finasteride is the active ingredient in Propecia®, an oral medication that’s clinically-proven to ...
Other 5α-reductase inhibitors such as finasteride (a type 2 inhibitor) have been used off-label to treat excessive hair growth in women with hirsutism. [ 3 ] [ 23 ] Since dutasteride is an inhibitor of both type 1 and 2 5α-reductases, it could theoretically be a more effective therapy for hirsutism.