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2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

   www.aol.com/tadalafil-ultimate-guide-dosages...

   Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours. Tadalafil 10mg: Typical ...

3. Tadalafil - Wikipedia

   en.wikipedia.org/wiki/Tadalafil

   Tadalafil. Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [5][6][8] It is taken by mouth. [8] Onset is typically within half an hour and the duration is up to 36 hours. [8]

4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

   www.aol.com/ed-pill-guide-everything-know...

   Many of these pills work fairly quickly. Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 ...

5. Weighing the Pros & Cons of 4 Common ED Pills - AOL

   www.aol.com/weighing-pros-cons-4-common...

   Over the last 25 years, (ED) medications such as Viagra and others have become common and normal pieces of bedroom tool kit. These little pills have helped hundreds of millions of men all over the ...

6. PDE5 inhibitor - Wikipedia

   en.wikipedia.org/wiki/PDE5_inhibitor

   A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues. These drugs dilate the corpora cavernosa of the penis, facilitating erection with ...

7. Discovery and development of phosphodiesterase 5 inhibitors

   en.wikipedia.org/wiki/Discovery_and_development...

   This allows for a longer therapeutic window and is therefore often a more convenient drug than others with a shorter therapeutic window. Tadalafil is more bioavailable (80%) than sildenafil (40%) and vardenafil (15%) but it has a slow absorption, or about 2 hours compared to 50 minutes of sildenfil. Vardenafil is most known for its potency. [24]