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Autologous stem cell transplants are used more often to treat lymphoma, but this may not be an option if the person's lymphoma has metastasized to their bone marrow or blood. Allogeneic stem cell transplants have side effects that can make it hard for the patient to tolerate the treatment. [39]
Autologous stem-cell transplantation is distinguished from allogenic stem cell transplantation where the donor and the recipient of the stem cells are different people. [2] It can be also used as an Assisted reproductive technology to improve the reproductive outcomes. In a first step the bone marrow derived stem cells are mobilized.
Severe suppression of the bone marrow, heightened vulnerability to infections, gastrointestinal toxicity, and more systemic problems were among the possible side effects. Autologous Stem Cell Transplantation (ASCT), which involves the collection and storage of a patient's own stem cells prior to the administration of HDC, plays a vital role in ...
Stem-cell transplantation was pioneered using bone marrow-derived stem cells by a team at the Fred Hutchinson Cancer Research Center from the 1950s through the 1970s led by E. Donnall Thomas, whose work was later recognized with a Nobel Prize in Physiology or Medicine. Thomas' work showed that bone-marrow cells infused intravenously could ...
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.
Cell therapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are injected, grafted or implanted into a patient in order to effectuate a medicinal effect, [1] for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or ...