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  2. 46,XX/46,XY - Wikipedia

    en.wikipedia.org/wiki/46,XX/46,XY

    Diagnosing a chimera or mosaic is particularly difficult due to the random distribution of 46,XX and 46,XY cells within the body. In a chimeric, an organ might be made up of a mix of 46,XX and 46,XY, but is made up entirely only one genotype. When that is the case, no abnormalities are noted and other types of tissues need to be analyzed. [15]

  3. Human chimera - Wikipedia

    en.wikipedia.org/wiki/Human_chimera

    A human chimera is a human with a subset of cells with a distinct genotype than other cells, that is, having genetic chimerism.In contrast, an individual where each cell contains genetic material from a human and an animal is called a human–animal hybrid, while an organism that contains a mixture of human and non-human cells would be a human-animal chimera.

  4. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    Zygosity (the noun, zygote, is from the Greek zygotos "yoked," from zygon "yoke") (/ z aɪ ˈ ɡ ɒ s ɪ t i /) is the degree to which both copies of a chromosome or gene have the same genetic sequence. In other words, it is the degree of similarity of the alleles in an organism.

  5. Chimera (genetics) - Wikipedia

    en.wikipedia.org/wiki/Chimera_(genetics)

    Two-colored rose chimera. A genetic chimerism or chimera (/ k aɪ ˈ m ɪər ə / ky-MEER-ə or / k ɪ ˈ m ɪər ə / kim-EER-ə) is a single organism composed of cells with more than one distinct genotype. Animal chimeras can be produced by the fusion of two (or more) embryos.

  6. Chimera (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Chimera_(molecular_biology)

    In molecular biology, and more importantly high-throughput DNA sequencing, a chimera is a single DNA sequence originating when multiple transcripts or DNA sequences get joined. Chimeras can be considered artifacts and be filtered out from the data during processing [ 1 ] to prevent spurious inferences of biological variation. [ 2 ]

  7. X-inactivation - Wikipedia

    en.wikipedia.org/wiki/X-inactivation

    When the egg (carrying X M), is fertilized by a sperm (carrying a Y or an X P) a diploid zygote forms. From zygote, through adult stage, to the next generation of eggs, the X chromosome undergoes the following changes: Xi P Xi M zygote → undergoing zygotic genome activation, leading to: Xa P Xa M → undergoing imprinted (paternal) X ...

  8. Glossary of cellular and molecular biology (M–Z) - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_cellular_and...

    A laboratory technique involving the use of a microscopic lance or nanopipette (typically about 100 nanometres in diameter) in the presence of an electric field in order to deliver DNA or RNA directly into a cell, often a zygote or early embryo, via an electrophoretic mechanism. While submerged in a pH-buffered solution, a positive electric ...

  9. Cleavage (embryo) - Wikipedia

    en.wikipedia.org/wiki/Cleavage_(embryo)

    In embryology, cleavage is the division of cells in the early development of the embryo, following fertilization. [1] The zygotes of many species undergo rapid cell cycles with no significant overall growth, producing a cluster of cells the same size as the original zygote.