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  2. Medial forebrain bundle - Wikipedia

    en.wikipedia.org/wiki/Medial_forebrain_bundle

    The medial forebrain bundle may serve as a target in treating treatment-resistant depression. [8] Since the MFB connects areas of the brain which are involved with motivated behavior, mood regulation, and antidepressant response the stimulation of the MFB through deep brain stimulation could be an effective form of treatment.

  3. Brain stimulation reward - Wikipedia

    en.wikipedia.org/wiki/Brain_stimulation_reward

    The lateral hypothalamus is a portion of the hypothalamus, and brain stimulation to this area at the level of the medial forebrain bundle produces the highest response rates and subsequently the highest reward potency in rodents. Lesions in this region or along its boundary cause a loss of positive drive-reward behaviors as well as all other ...

  4. Mesolimbic pathway - Wikipedia

    en.wikipedia.org/wiki/Mesolimbic_pathway

    It is one of the component pathways of the medial forebrain bundle, which is a set of neural pathways that mediate brain stimulation reward. [10] The VTA is located in the midbrain and consists of dopaminergic, GABAergic, and glutamatergic neurons. [11]

  5. Reward system - Wikipedia

    en.wikipedia.org/wiki/Reward_system

    The medial forebrain bundle, which is a set of many neural pathways that mediate brain stimulation reward (i.e., reward derived from direct electrochemical stimulation of the lateral hypothalamus), is also a component of the reward system. [24]

  6. List of regions in the human brain - Wikipedia

    en.wikipedia.org/wiki/List_of_regions_in_the...

    Medial forebrain bundle; Medial longitudinal fasciculus; Myoclonic triangle; Solitary tract; Major dopaminergic pathways from dopaminergic cell groups. Mesocortical pathway; Mesolimbic pathway; Nigrostriatal pathway; Tuberoinfundibular pathway; Serotonergic pathways. Raphe Nuclei; Norepinephrine Pathways Locus coeruleus and other noradrenergic ...

  7. Nigrostriatal pathway - Wikipedia

    en.wikipedia.org/wiki/Nigrostriatal_pathway

    The axons from dopamine neurons emanate from a primary dendrite and project ipsilaterally (on the same side) via the medial forebrain bundle to the dorsal striatum. There is a rough topographical correlation between the anatomical localization of the dopamine cell body within the SNc and the area of termination in the dorsal striatum.

  8. Limbic system - Wikipedia

    en.wikipedia.org/wiki/Limbic_system

    The limbic system, also known as the paleomammalian cortex, is a set of brain structures located on both sides of the thalamus, immediately beneath the medial temporal lobe of the cerebrum primarily in the forebrain. [1] Its various components support a variety of functions including emotion, behavior, long-term memory, and olfaction. [2]

  9. Dorsal longitudinal fasciculus - Wikipedia

    en.wikipedia.org/wiki/Dorsal_longitudinal_fasciculus

    A small ascending dorsal serotonergic pathway arising from the ventral and dorsal superior raphe nuclei initially travels in the DLF, with some of its fibres terminating in the periaqueductal gray of the midbrain, and the posterior hypothalamus; the majority of its fibers however pass beyond the DLF in the medial forebrain bundle, here uniting ...