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Coronary artery disease (CAD) or ischemic heart disease are the terms used to describe narrowing of the coronary arteries. [8] As the disease progresses, plaque buildup can partially block blood flow to the heart muscle. Without enough blood supply , the heart is unable to work properly, especially under increased stress.
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
[5] [6] Commonly, the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. [7] In a healthy heart, blood flows one way through the heart due to heart valves, which prevent backflow. [4] The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of ...
Interruptions of coronary circulation quickly cause heart attacks (myocardial infarctions), in which the heart muscle is damaged by oxygen starvation. Such interruptions are usually caused by coronary ischemia linked to coronary artery disease , and sometimes to embolism from other causes like obstruction in blood flow through vessels.
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [1] [2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).
[2] [5] It may also supply 25% to 35% of the left ventricle (LV). [10] There is significant overlap of supply of the coronary arteries. [2] The right coronary artery is dominant over the left coronary artery 50% of the time, equal to it 20% of the time, and less significant than it 30% of the time. [2]
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
The heart is located in the middle of the abdomen with its tip slightly towards the left side of the abdomen. Disorders of the heart lead to heart disease and cardiovascular disease and can lead to a significant number of deaths: cardiovascular disease is the leading cause of death in the U.S. and caused 24.95% of total deaths in 2008. [19]