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Bag and contents of a well-known early brand of synthetic cannabinoids named k2 spice that contains herbs covered with synthetic cannabinoids, now illegal throughout much of the world. Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants ...
HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol [2] by a group led by Raphael Mechoulam at the Hebrew University. [3] [4] [5] HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. [6]
AMB-FUBINACA (also known as FUB-AMB and MMB-FUBINACA [3]) is an indazole-based synthetic cannabinoid that is a potent agonist for the cannabinoid receptors, with K i values of 10.04 nM at CB 1 and 0.786 nM at CB 2 and EC 50 values of 0.5433 nM at CB 1 and 0.1278 nM at CB 2, [4] and has been sold online as a designer drug.
AB-FUBINACA (AMB-FUBINACA [2]) is a psychoactive drug that acts as a potent agonist for the cannabinoid receptors, with K i values of 0.9 nM at CB 1 and 23.2 nM at CB 2 and EC 50 values of 1.8 nM at CB 1 and 3.2 nM at CB 2.
CBN was the first cannabis compound to be isolated from cannabis extract in the late 1800s. Its structure and chemical synthesis were achieved by 1940 [ 34 ] , followed by some of the first pre-clinical research studies to determine the effects of individual cannabis-derived compounds in vivo . [ 35 ]
Dimethylheptylpyran (DMHP) is a synthetic cannabinoid and analogue of tetrahydrocannabinol (THC). It was invented in 1949 during attempts to elucidate the structure of Δ 9-THC, one of the active components of cannabis. [2] DMHP is a pale yellow, viscous oil which is insoluble in water but dissolves in alcohol or non-polar solvents.
Synthetic marijuana, commonly called "K2" or "spice," is especially popular in prison systems and jails across the country because it's cheap, easy to smuggle, and doesn't show up in routine urine ...
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