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Zinc L-carnosine (beta-alanyl-L-histidinato zinc [1]) (N-(3-aminopropionyl)-L-histidinato zinc [2]), often simply called zinc carnosine, and also known as polaprezinc, [3] is a mucosal protective [4] [5] chelate compound of zinc and L-carnosine invented by Hamari Chemicals, Ltd. [6] [7] It is a quadridentate 1:1 complex of a polymeric nature. [6]
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Treatments with iron(II) sulfate have higher incidence of adverse events than iron(III)-hydroxide polymaltose complex (IPC) [29] [30] [31] or iron bis-glycinate chelate. [32] [33] Iron overdose has been one of the leading causes of death caused by toxicological agents in children younger than six years. [34] Iron poisoning may result in ...
The term chelate (/ ˈ k iː l eɪ t /) was first applied in 1920 by Sir Gilbert T. Morgan and H. D. K. Drew, who stated: "The adjective chelate, derived from the great claw or chele (Greek) of the crab or other crustaceans, is suggested for the caliperlike groups which function as two associating units and fasten to the central atom so as to ...
Carnosine (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues. [citation needed] Carnosine was discovered by Russian chemist Vladimir Gulevich. [1] Carnosine is naturally produced by the body in the liver [2] from beta-alanine and histidine.