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  2. Castell's sign - Wikipedia

    en.wikipedia.org/wiki/Castell's_sign

    To rule out an enlarged spleen, a pretest probability of 30% or less will yield a negative predictive value over 90% (calculation) Given the paucity of physical exam findings to evaluate possible splenomegaly, Castell's sign is the most sensitive, and is thus a good tool to teach in an advanced-type physical diagnosis course.

  3. Splenomegaly - Wikipedia

    en.wikipedia.org/wiki/Splenomegaly

    Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...

  4. Hepatosplenomegaly - Wikipedia

    en.wikipedia.org/wiki/Hepatosplenomegaly

    Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.

  5. Abdominal examination - Wikipedia

    en.wikipedia.org/wiki/Abdominal_examination

    Depending on the need to test for specific diseases such as ascites, special tests may be performed as a part of the physical examination. [2] An abdominal examination may be performed because the physician suspects a disease of the organs inside the abdominal cavity (including the liver, spleen, large or small intestines), or simply as a part ...

  6. Signs and symptoms - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms

    Signs (including enlarged liver and spleen) and symptoms (including headache and vomiting) of acute HIV infection Signs and symptoms are diagnostic indications of an illness , injury, or condition. Signs are objective and externally observable; symptoms are a person's reported subjective experiences.

  7. Organomegaly - Wikipedia

    en.wikipedia.org/wiki/Organomegaly

    Spleen: Splenomegaly: Medical imaging: Largest dimension of over 11 cm, [27] [28] or craniocaudal height of 13 [29] cm. Moderate splenomegaly: the largest dimension is between 11–20 cm [27] Severe splenomegaly: the largest dimension is greater than 20 cm [27] Autopsy: Weight over upper limit of standard reference range, of 230 g (8.1 oz) [12 ...

  8. Tropical splenomegaly syndrome - Wikipedia

    en.wikipedia.org/wiki/Tropical_splenomegaly_syndrome

    The spleen is massively enlarged. It shows dilated sinusoids lined with reticulum cells. There is a marked erythrophagocytosis and lymphocytic infiltration of the pulp. Peripheral smear for malarial parasite is usually negative. Condition may show features of hypersplenism in severe form like anemia and thrombocytopenia.

  9. Nixon's sign - Wikipedia

    en.wikipedia.org/wiki/Nixon's_sign

    The patient is first placed in the right lateral decubitus position. Percussion starts at the midpoint of the left costal margin and is continued upward perpendicular to the left costal margin.