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Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954.
AST exists in two isoenzymes namely mitochondrial form and cytoplasmic form. It is found in highest concentration in the liver, followed by heart, muscle, kidney, brain, pancreas, and lungs. [ 10 ] This wide range of AST containing organs makes it a relatively less specific indicator of liver damage compared to ALT.
In general, any damage to the liver will cause medium elevations in these transaminases, but diagnosis requires synthesis of many pieces of information, including the patient's history, physical examination, and possibly imaging or other laboratory examinations.
Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [1]
View history; Tools. Tools. ... is a blood test consisting of a set of seven or eight biochemical tests and is one of the most common lab tests ... AST/ALT = 0.6 BU ...
If Rocket Lab, Planet Labs, and AST SpaceMobile aren't going to rise with a rising market, or enjoy turbocharged growth from low or falling interest rates, then investors are going to have to ...
AST Research, Inc., as known as AST Computer, a personal computer manufacturer; Asti, Italian province and city (was traditionally Ast in the Piemontese dialect) Assured shorthold tenancy, UK; Asturian language (ISO 639 alpha-3: ast), Spain; Astana Pro Team (UCI code AST), a professional road bicycle racing team
The comprehensive metabolic panel, or chemical screen (CMP; CPT code 80053), is a panel of 14 blood tests that serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance, but this type of screening has its limitations.