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Pterostilbene is considered to be a corrosive substance, is dangerous upon exposure to the eyes, and is an environmental toxin, especially to aquatic life. [1] A preliminary study of healthy human subjects given pterostilbene for 6–8 weeks, showed pterostilbene to be safe for human use at dosages up to 250 mg per day, although this study did not assess metabolic effects on the lipid profile.
Human Longevity, Inc. is a San Diego–based venture launched by Craig Venter, Robert Hariri and Peter Diamandis in 2013. Its goal is to build the world's most comprehensive database on human genotypes and phenotypes, and then subject it to machine learning so that it can help develop new ways to fight diseases associated with aging . [ 1 ]
A 2009 review of longevity research noted: "Extrapolation from worms to mammals is risky at best, and it cannot be assumed that interventions will result in comparable life extension factors. Longevity gains from dietary restriction, or from mutations studied previously, yield smaller benefits to Drosophila than to nematodes, and smaller still ...
ChromaDex is a dietary supplement and food ingredient company based in Los Angeles, California founded in 1999 that is publicly traded on the NASDAQ.. In 2011, ChromaDex licensed patents from Dartmouth College, Cornell University, and Washington University in St. Louis regarding nicotinamide riboside, which it markets and sells as an ingredient under the brand name Niagen.
It is a gel based on an onion extract. Mederma is product of HRA Pharma, a division of Perrigo . A Mederma marketing claim is that the product can can make scars "softer, smoother, and less noticeable".
In 2015, Elysium introduced its first product, Basis, which contains nicotinamide riboside and pterostilbene. [2] [3] In December 2016, Elysium received an investment of $20 million in Series B funding. [4] [5] In 2019, Elysium introduced a test called Index that uses epigenetic analysis on saliva samples to estimate biological age. [6] [7]