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  2. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    FNA of the abdominal fat pad shows amyloid deposits in 70-75% of cases of suspected AL amyloidosis and diagnosed 85% of cases when combined with a bone marrow biopsy. [4] Other peripheral areas such as the salivary glands, gingiva, rectum or skin may also be biopsied, however in some cases a biopsy of the target organ may be needed. [4]

  3. Amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Amyloidosis

    Amyloid light chains deposition in shoulder joint causes enlarged shoulders, also known as "shoulder pad sign". [18] Amyloid light chain depositions can also cause bilateral symmetric polyarthritis. [18] The deposition of amyloid proteins in the bone marrow without causing plasma cell dyscrasias is called amyloidoma. It is commonly found in ...

  4. Cardiac amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Cardiac_amyloidosis

    Following chemotherapy, a bone marrow transplant can be utilized to restore the normal cell lines. [5] There are newer medications (ixazomib, carfilzomib, daratumumab, elotuzumab) under research for the treatment of multiple myeloma that can help to decrease the production of free light chains. [5]

  5. Young bone marrow transplants may help fight Alzheimer's ...

    www.aol.com/lifestyle/young-bone-marrow...

    In particular, bone marrow transplant restored the ability of monocytes to eliminate amyloid-beta build up, reducing cerebral and plasma amyloid-beta levels in the 9-month-old mice that had ...

  6. AA amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AA_amyloidosis

    AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose plasma concentration is highest ...

  7. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    Myeloma bone disease is due to the overexpression of receptor activator for nuclear factor κ B ligand by bone marrow stroma. RANKL activates osteoclasts , which resorb bone. The resultant bone lesions are lytic (cause breakdown) in nature, and are best seen in plain radiographs, which may show "punched-out" resorptive lesions (including the ...

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