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Choline deficiency can cause fatty liver, which increases cancer and cardiovascular disease risk. Choline deficiency also decreases SAM production, which partakes in DNA methylation – this decrease may also contribute to carcinogenesis. Thus, deficiency and its association with such diseases has been studied. [6]
The main complication resulting from pseudocholinesterase deficiency is the possibility of respiratory failure secondary to succinylcholine or mivacurium-induced neuromuscular paralysis. Individuals with pseudocholinesterase deficiency also may be at increased risk of toxic reactions, including sudden cardiac death, associated with recreational ...
Vitamin D deficiency. Signs of vitamin deficiency include bone pain, fatigue, muscle weakness, aches or cramps, and mood changes, like depression, according to Cleveland Clinic. Vitamin B12 deficiency
In the case of long-term total-parenteral-nutrition-induced fatty liver disease, choline has been shown to alleviate symptoms. [ 36 ] [ 37 ] [ 38 ] This may be due to a deficiency in the methionine cycle .
News research suggests that consuming a moderate amount of choline through foods such as eggs, cabbage, and shiitake mushrooms could help reduce the risk of atherosclerotic heart disease.
In general, the word "choline" describes the various quaternary ammonium salts containing the N,N,N-trimethylethanolammonium cation. Found in most animal tissues, choline is a primary component of the neurotransmitter acetylcholine and functions with inositol as a basic constituent of lecithin. Choline also prevents fat deposits in the liver ...
Diet and supplement use should be overseen by medical professionals and nutritionists, as dietary restrictions can have other serious adverse health effects. Choline in particular is an essential nutrient required for proper neural formation in foetal and childhood development, if pregnant or breast-feeding a low choline diet should be avoided.
[35] [36] Choline deficiency can lead to the development of MASLD. [37] Higher consumption of processed, red, and organ meats have been associated with higher risk of developing MASLD. [38] [39] [40] Some research also suggests eggs are also associated with developing MASLD.