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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer ...
Signs and symptoms are not mutually exclusive, for example a subjective feeling of fever can be noted as sign by using a thermometer that registers a high reading. [7] Because many symptoms of cancer are gradual in onset and general in nature, cancer screening (also called cancer surveillance) is a key public health priority. This may include ...
Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
Lung cancer is more frequent if the tripe palms present alone, whereas cancer of the stomach is more frequent when AN is also present. [1] The sign has also been associated with bullous pemphigoid, psoriasis, and exfoliative dermatitis. [2] It is believed that growth factors secreted by cancer cells cause some skin cells to grow. [3]
These papulonodules begin on the extremities, especially on the dorsa of the hands and the wrists and may disseminate to involve the entire body, including the face. [8] The papulonodules may vary in size from 2–3 mm to 10 mm in diameter. Pruritus is often associated. Florid cutaneous papillomatosis is linked with an underlying cancer.
RS3PE has been documented in patients with cancers (Non-Hodgkin's lymphoma, gastric cancer, pancreatic cancer, lung cancer, breast cancer, colon cancer, prostate cancer and bladder cancer, among others), in whom it might represent a paraneoplastic manifestation. [10] [11] [12] Other underlying disorders include vasculitides such as ...
According to Know Your Lemons, a nonprofit global organization that focuses on making information about breast cancer warning signs and detection methods accessible, a hard lump is a common sign ...
Vinca alkaloids induce sensorimotor neuropathy, decreased sensation, in the hands and feet. Symptoms of vinca alkaloids include muscle weakness, initial pain after receiving an infusion, and cramping. These symptoms usually appear within the first three months of treatment. Of the vinca alkaloids, the most neurotoxic drug is vincristine.