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Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Co-trimoxazole is the recommended standard treatment for whipple's disease in some treatment protocols. [54] [55] [56] Fungal and protozoal infections: Isosporiasis: No: No: No: Clinical trials have confirmed its use in this indication. [57] Malaria: No: No: No: Clinical trials have confirmed its efficacy in both the treatment and prevention of ...
Treatment of Clostridioides (formerly Clostridium) difficile infection. [8] May be more narrow-spectrum than vancomycin, resulting in less bowel microbiota alteration. [9] Nausea (11%), vomiting, and abdominal pain. [10] Bactericidal in susceptible organisms such as C. difficile by inhibiting RNA polymerase, thereby inhibiting protein synthesis ...
Perianal cellulitis manifests as multiple symptoms that are inconsistent with a systemic disease. The most notable feature is a very distinct redness around the anus, and other signs of inflammation which can include swelling and itching at the site. [4] Other associated symptoms with perianal cellulitis include pain when defecating and
A colored electron microscopy image of methicillin-resistant staphylococcus aureus (), a bacterium commonly targeted by broad-spectrum antibioticsA broad-spectrum antibiotic is an antibiotic that acts on the two major bacterial groups, Gram-positive and Gram-negative, [1] or any antibiotic that acts against a wide range of disease-causing bacteria. [2]
Cellulitis is usually [9] a bacterial infection involving the inner layers of the skin. [1] It specifically affects the dermis and subcutaneous fat. [1] Signs and symptoms include an area of redness which increases in size over a few days. [1] The borders of the area of redness are generally not sharp and the skin may be swollen. [1]
Doxycycline is a broad-spectrum antibiotic that is employed in the treatment of numerous bacterial infections. It is effective against bacteria such as Moraxella catarrhalis, Brucella melitensis, Chlamydia pneumoniae, and Mycoplasma pneumoniae. Additionally, doxycycline is used in the prevention and treatment of serious conditions like anthrax ...
Antibiotic combinations are increasingly important because of antimicrobial resistance. [2] This means that individual antibiotics that used to be effective are no longer effective, [ 1 ] and because of the absence of new classes of antibiotic, they allow old antibiotics to be continue to be used. [ 2 ]