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The report found that Merck's senior management acted in good faith, and that the confusion over the clinical safety of Vioxx was due to the sales team's overzealous behavior. The report that was filed gave a timeline of the events surrounding Vioxx and stated that Merck intended to operate honestly throughout the process.
Withdrawn from US in 2005 due to hepatotoxicity. [41] [3] Pentobarbital: 1980 Norway Risk of fatal overdose. [3] Pentylenetetrazol: 1982 US Withdrawn for inability to produce effective convulsive therapy, and for causing seizures. Pergolide (Permax) 2007 US Risk for heart valve damage. [2] Perhexiline: 1985 UK, Spain Neurologic and hepatic ...
The VIGOR (Vioxx Gastrointestinal Outcomes Research) trial, "which was the making of Merck's drug rofecoxib (Vioxx)," [46] was at the center of a dispute about the ethics of medical journals. In the VIGOR trial, over 8,000 patients were randomized to receive either naproxen or rofecoxib (Vioxx).
At least three people have died due to a rare bacteria found in recalled eye drops, distributed by Ezricare and Delsam Pharma, according to the CDC. There have also been cases of vision loss ...
Here’s what you need to know about each product and why they’re on the recall list. ... TreeHouse Foods issued the recall due to contamination concerns in waffles purchased between Oct. 13 and ...
[5] [6] It took less than eight years to develop and market the first COX-2 inhibitor, with Celebrex launched in December 1998 and Vioxx launched in May 1999. [7] [8] Celecoxib and other COX-2 selective inhibitors, valdecoxib, parecoxib, and mavacoxib, were discovered by a team at the Searle division of Monsanto led by John Talley.
There’s an active recall on various brands of bread and buns in Canada, according to the Canadian Food Inspection Agency. This is due to pieces of metal being found in the affected product.
This increase in 2016 is even more marked when looking at the number of products recalled (as opposed to recall event) due to foreign body contamination. In 2016 there were 422 products recalled due to foreign body contamination, whilst in 2015 there were 108; almost a 300% increase.