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Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8] It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them. [7] [9] Side effects include rash and irritation where it is applied. [8]
Treatment: Permethrin is the drug of choice for the treatment of scabies, per the CDC. Topical permethrin should be applied every two to three days for up to two weeks.
First choice drug. Permethrin exerts its therapeutic effect by disrupting sodium transport across neuronal membranes in arthropods, inducing depolarization. This mechanism ultimately leads to respiratory paralysis in the affected arthropod, establishing permethrin as a potent agent in managing scabies and pediculosis. [4]
A study has demonstrated that scabies is markedly reduced in populations taking ivermectin regularly; [51] the drug is widely used for treating scabies and other parasitic diseases, particularly among the poor and disadvantaged in the tropics, beginning with the developer Merck providing the drug at no cost to treat onchocerciasis from 1987. [52]
As a medication it is used to treat scabies and lice. [2] For scabies either permethrin or malathion is typically preferred. [3] It is applied to the skin as a lotion. [2] Typically two to three applications are needed. [2] It is also present in Balsam of Peru, Tolu balsam, and in a number of flowers. [4] Side effects may include irritation of ...
Cypermethrin is moderately toxic through skin contact or ingestion. It may cause irritation to the skin and eyes. Symptoms of dermal exposure include numbness, tingling, itching, burning sensation, loss of bladder control, incoordination, seizures and possible death.