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Chloramphenicol may cause bone marrow suppression during treatment; this is a direct toxic effect of the drug on human mitochondria. [23] This effect manifests first as a fall in hemoglobin levels, which occurs quite predictably once a cumulative dose of 20 g has been given. The anaemia is fully reversible once the drug is stopped and does not ...
human: Y: treatment of Zaire ebolavirus (Ebola virus) Atorolimumab [2] mab: human: Rhesus factor: hemolytic disease of the newborn [citation needed] Avelumab [12] Bavencio: mab: human: PD-L1: Y: cancer Axatilimab [27] Niktimvo: mab: humanized: CSF1R: Y: chronic graft-versus-host disease: Azintuxizumab vedotin [28] mab: chimeric/ humanized ...
Examples of amphenicols include chloramphenicol, thiamphenicol, azidamfenicol, and florfenicol. The first-in-class compound was chloramphenicol, introduced in 1949. Chloramphenicol was initially discovered as a natural product and isolated from the soil bacteria Streptomyces venezuelae; [2] however, all amphenicols are now made by chemical ...
A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. A substance recognized by an official pharmacopeia or formulary . Biological products are included within this definition and are generally covered by the same laws and regulations, but differences exist regarding their manufacturing processes ...
Chloramphenicol — formerly first-line therapy for Rocky Mountain spotted fever (until doxycycline became available). [4] Also first-line therapy (used topically) for bacterial conjunctivitis , and systemically for meningitis when allergies to penicillin or cephalosporin exist.
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