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  2. Model for End-Stage Liver Disease - Wikipedia

    en.wikipedia.org/wiki/Model_for_End-Stage_Liver...

    The Model for End-Stage Liver Disease, or MELD, is a scoring system for assessing the severity of chronic liver disease.It was initially developed to predict mortality within three months of surgery in patients who had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure, [1] and was subsequently found to be useful in determining prognosis and prioritizing for receipt of ...

  3. Alcoholic liver disease - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_liver_disease

    Risk factors known as of 2010 are: Quantity of alcohol taken: Consumption of 60–80 g per day (14 g is considered one standard drink in the US, e.g. 1 + 1 ⁄ 2 US fl oz or 44 mL hard liquor, 5 US fl oz or 150 mL wine, 12 US fl oz or 350 mL beer; drinking a six-pack of 5% ABV beer daily would be 84 g and just over the upper limit) for 20 years or more in men, or 20 g/day for women ...

  4. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    The AST/ALT ratio increases in liver functional impairment. In alcoholic liver disease, the mean ratio is 1.45, and mean ratio is 1.33 in post necrotic liver cirrhosis. Ratio is greater than 1.17 in viral cirrhosis, greater than 2.0 in alcoholic hepatitis, and 0.9 in non-alcoholic hepatitis.

  5. Cirrhosis - Wikipedia

    en.wikipedia.org/wiki/Cirrhosis

    Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, chronic liver failure or chronic hepatic failure and end-stage liver disease, is an acute condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue and regenerative nodules as a result of chronic liver disease.

  6. Survival analysis - Wikipedia

    en.wikipedia.org/wiki/Survival_analysis

    Survival random forest analysis is available in the R package "randomForestSRC". [10] The randomForestSRC package includes an example survival random forest analysis using the data set pbc. This data is from the Mayo Clinic Primary Biliary Cirrhosis (PBC) trial of the liver conducted between 1974 and 1984.

  7. Child–Pugh score - Wikipedia

    en.wikipedia.org/wiki/Child–Pugh_score

    3 points Total bilirubin, μmol/L (mg/dL) < 34 (< 2) 34–50 (2–3) > 50 (> 3) Serum albumin, g/dL > 3.5 2.8–3.5 < 2.8 OR Prothrombin time, prolongation (s) < 4.0: 4.0–6.0 > 6.0: INR < 1.7 1.7–2.3 > 2.3 Ascites: None Mild (or suppressed with medication) Moderate to severe (or refractory) Hepatic encephalopathy: None Grade I–II Grade ...

  8. Alcoholic hepatitis - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_hepatitis

    10-20% of patients with alcoholic hepatitis progress to alcoholic liver cirrhosis every year. [10] Patients with liver cirrhosis develop liver cancer at a rate of 1.5% per year. [11] In total, 70% of those with alcoholic hepatitis will go on to develop alcoholic liver cirrhosis in their lifetimes. [10]

  9. Acute liver failure - Wikipedia

    en.wikipedia.org/wiki/Acute_liver_failure

    Other series have reported death rates of those listed for transplant as high as 40%. In the ALFSG, the transplantation rate was higher in the groups with lower short-term spontaneous survival, making overall survival similar in all groups: acetaminophen, 73%; drug induced, 70%; indeterminate group, 64%; and other causes, 61%.