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Fasciolopsiasis results from an infection by the trematode Fasciolopsis buski, [1] the largest intestinal fluke of humans, growing up to 7.5 cm (3.0 in) long.
Despite that fact, faecal examination is still the only used diagnostic tool in some countries. While coprological diagnosis of fasciolosis is possible from 8- to 12 weeks post-infection (WPI), F. hepatica specific-antibodies are recognized using ELISA or Western blot after 2-4 weeks post-infection.
Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode (fluke or flatworm, a type of helminth) of the class Trematoda, phylum Platyhelminthes.
Fasciolopsis buski is the cause of the pathological condition fasciolopsiasis. [3] In London, George Busk first described Fasciolopsis buski in 1843 after finding it in the duodenum of a sailor. After years of careful study and self experimentation, in 1925, Claude Heman Barlow determined its life cycle in humans. [4] [5] [6]
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Fasciola gigantica causes outbreaks in tropical areas of South Asia, Southeast Asia, and Africa.The geographical distribution of F. gigantica overlaps with F. hepatica in many African and Asian countries and sometimes in the same country, although in such cases, the ecological requirement of the flukes and their snail hosts are distinct.