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Models and simulation setups (so-called Applications) can be stored in local files as Virtual Cell Markup Language (VCML) [9] or stored remotely in the VCell database. Models can be imported and exported as Systems Biology Markup Language (SBML) [10]
The Virtual Physiological Rat (VPR) Project [1] [2] [3] is an international collaboration aimed at simulating the integrated cardiovascular function of the rat and supported by the National Institute of General Medical Sciences as a National Center for Systems Biology. The project is motivated by the fact that, although there exist both a depth ...
PhET Interactive Simulations is part of the University of Colorado Boulder which is a member of the Association of American Universities. [10] The team changes over time and has about 16 members consisting of professors, post-doctoral students, researchers, education specialists, software engineers (sometimes contractors), educators, and administrative assistants. [11]
Biosimulation is becoming increasingly important for drug development. [1] Since on average only 11% of all drug candidates are approved, [2] it is anticipated that biosimulation may be the tool to predict whether a candidate drug will fail in the development process e.g. in clinical trials due to adverse side effects, bad pharmacokinetics or even toxicity.
The initial concepts that led to the Virtual Physiological Human initiative came from the IUPS Physiome Project.The project was started in 1997 and represented the first worldwide effort to define the physiome through the development of databases and models which facilitated the understanding of the integrative function of cells, organs, and organisms. [7]
OpenWorm is an international open science project for the purpose of simulating the roundworm Caenorhabditis elegans at the cellular level. [1] [2] [3] Although the long-term goal is to model all 959 cells of the C. elegans, the first stage is to model the worm's locomotion by simulating the 302 neurons and 95 muscle cells.
Virtual Labs is a project initiated by the Ministry of Education, Government of India, under the National Mission on Education through Information and Communication Technology. [1] The project aims to provide remote access to Laboratories in various disciplines of Science and Engineering for students at all levels from undergraduate to research.
Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems.