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Haemophilia A; Other names: Hemophilia A: Protein structure of coagulation factor VIII, of which its deficiency is the cause of haemophilia A. Specialty: Haematology: Symptoms: Prolonged bleeding from common injuries [1] Causes: Factor VIII deficiency [2] Diagnostic method: Bleeding time, [2] coagulation screen, genetic testing: Prevention
The second leading cause of death related to severe haemophilia complications is intracranial haemorrhage which today accounts for one third of all deaths of people with haemophilia. Two other major causes of death include hepatitis infections causing cirrhosis and obstruction of air or blood flow due to soft tissue haemorrhage.
Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII. These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding ...
2157 14069 Ensembl ENSG00000185010 ENSMUSG00000031196 UniProt P00451 Q06194 RefSeq (mRNA) NM_000132 NM_019863 NM_001161373 NM_001161374 NM_007977 RefSeq (protein) NP_000123 NP_063916 NP_001154845 NP_001154846 NP_032003 Location (UCSC) Chr X: 154.84 – 155.03 Mb Chr X: 74.22 – 74.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Coagulation factor VIII (Factor VIII, FVIII, also ...
Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause . Recurrent thrombosis: Hemophilia: Hemophilia A: Hemophilia B: Hemophilia C: Von Willebrand disease: Antiphospholipid syndrome: Thrombocytopenia: Glanzmann's thrombasthenia: Wiskott–Aldrich syndrome
Contaminated hemophilia blood products were a serious public health problem in the late 1970s up to 1985. [citation needed] Hemophilia A causes a deficiency in Factor VIII, a protein required for blood clotting. Factor VIII injections are a common treatment to prevent or stop bleeding in people with hemophilia A. [1]
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