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The open field is an arena with walls to prevent escape. Commonly, the field is marked with a grid and square crossings. The center of the field is marked with a different color to differentiate from the other squares. In the modern open field apparatus, infrared beams or video cameras with associated software can be used to automate the ...
The test rather reflects the anxiolytic effects of antidepressants and the response is seen only after chronic treatment with antidepressants. Elevated plus maze. Open field: [38] Rodents tend to avoid brightly illuminated areas, and this avoidance is interpreted as a symptom of anxiety. Open field is a bright enclosure and during the test ...
The LDB apparatus has two compartments. The light compartment is 2/3 of the box and is brightly lit and open. The dark compartment is 1/3 of the total box and is covered and dark. A door of 7 cm connects the two compartments. [2] Rodents prefer darker areas over lighter areas.
The test uses an elevated, plus-shaped (+) apparatus with two open and two enclosed arms. The behavioral model is based on the general aversion of rodents to open spaces. This aversion leads to thigmotaxis : a preference for remaining in enclosed spaces or close to the edges of a bounded space.
The term "behavioural despair test" bears an anthropomorphic connotation and is a somewhat subjective description as it is uncertain whether the test reliably gauges mood or despair. Strictly speaking, the descriptive term "forced swimming test" is preferred by researchers. [ 8 ]
During his first tests, he placed around 32 to 56 rats in a 10-by-14-foot (3.0 m × 4.3 m) cage in a barn in Montgomery County. He separated the space into four rooms. Every room was specifically created to support a dozen matured brown Norwegian rats. Rats could maneuver between the rooms by using the ramps.
The test was first developed by Dr. Carol Barnes in 1979. [1] The test subjects are usually rodents such as mice or lab rats , which either serve as a control or may have some genetic variable or deficiency present in them which will cause them to react to the maze differently.
The test was developed to study spatial learning and how it differed from other forms of associative learning. [11] Originally rats, now more commonly mice, were placed in an open pool and the latency to escape was measured for up to six trials a day for 2–14 days. [12] Several variables are used to evaluate an animal's performance.