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Fluticasone propionate is broken down by CYP3A4 (cytochrome P450 3A4), and has been shown to interact with strong CYP3A4 inhibitors such as ritonavir and ketoconazole. [2] [3] Coadministration of ritonavir and fluticasone may lead to increased levels of fluticasone in the body, which may lead to Cushing's Syndrome and adrenal insufficiency. [22]
Fluticasone furoate is indicated for the treatment of the symptoms of allergic rhinitis, [8] and asthma. [6] [7] Fluticasone Furoate is a corticosteroid medication primarily used to treat allergic rhinitis (hay fever) and non-allergic (perennial) rhinitis. It is also indicated for the treatment of nasal polyps in adults.
A common drug from this example can be found is Seretide®, containing a long-acting β-2 adrenergic receptor agonist named as Salmeterol and a corticosteroid named as Fluticasone. [25] Additive interaction can also be found in combination therapy for treating hypertension.
This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
Other side effects from this drug combination may include increased blood pressure, change in heart rate, an irregular heartbeat, increased risk of osteoporosis, cataracts, and glaucoma. [2] Studies have demonstrated the safety of inhaled fluticasone propionate in children.
Fluticasone is a manufactured glucocorticoid used to treat nasal congestion. [1] [2] [3] [4] [5] Both the esters, fluticasone propionate (sold as Flovent) and ...
Fluticasone furoate/umeclidinium bromide/vilanterol may have drug–drug interactions (DDIs) that are both pharmacokinetic (related to metabolism) and pharmacodynamic (related to the effect of medications) in nature. FF/UMEC/VI is susceptible to DDIs that would normally arise from any of the individual components of the medication.
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds: