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To prevent gout or a gout flare-up, try the following: Focus on eating a healthy, balanced diet, such as the Mediterranean way of eating or DASH (dietary approaches to stop hypertension)
Gout occurs more commonly in those who regularly drink beer or sugar-sweetened beverages; eat foods that are high in purines such as liver, shellfish, or anchovies; or are overweight. [ 1 ] [ 3 ] Diagnosis of gout may be confirmed by the presence of crystals in the joint fluid or in a deposit outside the joint . [ 1 ]
This occurs from a combination of diet, other health problems, and genetic factors. [3] [2] At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout. [3]
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Colchicine is a medication used to prevent and treat gout, [3] [4] to treat familial Mediterranean fever [5] and Behçet's disease, [6] and to reduce the risk of myocardial infarction. [7] The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout.
Gout can occur where serum uric acid levels are as low as 6 mg per 100 mL (357 μmol/L), but an individual can have serum values as high as 9.6 mg per 100 mL (565 μmol/L) and not have gout. [ 18 ] In humans, purines are metabolized into uric acid, which is then excreted in the urine.