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A conservative replacement (also called a conservative mutation or a conservative substitution or a homologous replacement) is an amino acid replacement in a protein that changes a given amino acid to a different amino acid with similar biochemical properties (e.g. charge, hydrophobicity and size). [1] [2]
A ring R is called a Jacobson ring if the nilradical and Jacobson radical of R/P coincide for all prime ideals P of R. An Artinian ring is Jacobson, and its nilradical is the maximal nilpotent ideal of the ring. In general, if the nilradical is finitely generated (e.g., the ring is Noetherian), then it is nilpotent.
Amino acid replacement is a change from one amino acid to a different amino acid in a protein due to point mutation in the corresponding DNA sequence. It is caused by nonsynonymous missense mutation which changes the codon sequence to code other amino acid instead of the original.
In other words, a very small change in stimulus causes a very large change in response, producing a sigmoidal dose-response curve. An ultrasensitive response is described by the general equation V = S n /(S n + K m), known as the Hill equation, when n, the Hill coefficient, is more than 1. The steepness of the sigmoidal curve depends on the ...
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
DNA may be modified, either naturally or artificially, by a number of physical, chemical and biological agents, resulting in mutations. Hermann Muller found that "high temperatures" have the ability to mutate genes in the early 1920s, [2] and in 1927, demonstrated a causal link to mutation upon experimenting with an x-ray machine, noting phylogenetic changes when irradiating fruit flies with ...
If R is commutative, the Jacobson radical always contains the nilradical. If the ring R is a finitely generated Z-algebra, then the nilradical is equal to the Jacobson radical, and more generally: the radical of any ideal I will always be equal to the intersection of all the maximal ideals of R that contain I. This says that R is a Jacobson ring.
3' untranslated region (3'-UTR). Also three-prime untranslated region, 3' non-translated region (3'-NTR), and trailer sequence.. 3'-end. Also three-prime end.. One of two ends of a single linear strand of DNA or RNA, specifically the end at which the chain of nucleotides terminates at the third carbon atom in the furanose ring of deoxyribose or ribose (i.e. the terminus at which the 3' carbon ...