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Amino acid replacement is a change from one amino acid to a different amino acid in a protein due to point mutation in the corresponding DNA sequence. It is caused by nonsynonymous missense mutation which changes the codon sequence to code other amino acid instead of the original.
A conservative replacement (also called a conservative mutation or a conservative substitution or a homologous replacement) is an amino acid replacement in a protein that changes a given amino acid to a different amino acid with similar biochemical properties (e.g. charge, hydrophobicity and size). [1] [2]
A ring R is called a Jacobson ring if the nilradical and Jacobson radical of R/P coincide for all prime ideals P of R. An Artinian ring is Jacobson, and its nilradical is the maximal nilpotent ideal of the ring. In general, if the nilradical is finitely generated (e.g., the ring is Noetherian), then it is nilpotent.
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
If R is commutative, the Jacobson radical always contains the nilradical. If the ring R is a finitely generated Z-algebra, then the nilradical is equal to the Jacobson radical, and more generally: the radical of any ideal I will always be equal to the intersection of all the maximal ideals of R that contain I. This says that R is a Jacobson ring.
Experimental biology is the set of approaches in the field of biology concerned with the conduction of experiments to investigate and understand biological phenomena. The term is opposed to theoretical biology which is concerned with the mathematical modelling and abstractions of the biological systems.
In other words, a very small change in stimulus causes a very large change in response, producing a sigmoidal dose-response curve. An ultrasensitive response is described by the general equation V = S n /(S n + K m), known as the Hill equation, when n, the Hill coefficient, is more than 1. The steepness of the sigmoidal curve depends on the ...
Radical elimination can be viewed as the reverse of radical addition. In radical elimination, an unstable radical compound breaks down into a spin-paired molecule and a new radical compound. Shown below is an example of a radical elimination reaction, where a benzoyloxy radical breaks down into a phenyl radical and a carbon dioxide molecule. [7]