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Acute toxicity describes the adverse effects of a substance that result either from a single exposure [1] or from multiple exposures in a short period of time (usually less than 24 hours). [ 2 ] To be described as acute toxicity, the adverse effects should occur within 14 days of the administration of the substance.
The maximum acceptable toxicant concentration (MATC) is a value that is calculated through aquatic toxicity tests to help set water quality regulations for the protection of aquatic life. Using the results of a partial life-cycle chronic toxicity test, the MATC is reported as the geometric mean between the No Observed Effect Concentration ...
Although acute or less observable chronic poisoning can also occur in non-target organisms (secondary poisoning), including the humans who apply the biocides and other beneficial organisms. [14] For example, the herbicide 2,4-D imitates the action of a plant hormone, which makes its lethal toxicity specific to plants. Indeed, 2,4-D is not a ...
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. [1] Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity).
Acute Exposure Guideline Levels; Acute inhalation injury; Acute to chronic ratio; Acute toxicity; Adverse outcome pathway; Aluminium toxicity in people on dialysis; Ammonia; Amurca; Antagonism (chemistry) Antimycin A; Antireticular cytotoxic serum; Aquatic toxicology databases; Arsenic poisoning; Asphyxiant gas; Automatism (toxicology)
Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
Acute toxicity (skull and crossbones) Hazardous to environment (dead tree and fish) Health hazard/hazardous to the ozone layer (exclamation mark) Serious health hazard (cross on a human silhouette) Gas under pressure (gas cylinder) These pictographs are also subdivided into class and categories for each classification. [13]
Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices.