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This list of protein subcellular localisation prediction tools includes software, databases, and web services that are used for protein subcellular localization prediction. Some tools are included that are commonly used to infer location through predicted structural properties, such as signal peptide or transmembrane helices , and these tools ...
The aim is to build tools that can accurately predict the outcome of protein targeting in cells. Prediction of protein subcellular localization is an important component of bioinformatics based prediction of protein function and genome annotation, and it can aid the identification of drug targets.
Proteome Analyst (PA) is a freely available web server and online toolkit for predicting protein subcellular localization, or where a protein resides in a cell. [1] [2] In the field of proteomics, accurately predicting a protein's subcellular localization, or where a specific protein is located inside a cell, is an important step in the large scale study of proteins.
LocDB [1] is an expert-curated database that collects experimental annotations for the subcellular localization of proteins in Homo sapiens (human) and Arabidopsis thaliana (Weed). The database also contains predictions of subcellular localization from a variety of state-of-the-art prediction methods for all proteins with experimental information.
The list of bioinformatics software tools can be split up according to the license used: List of proprietary bioinformatics software; List of open-source bioinformatics software; Alternatively, here is a categorization according to the respective bioinformatics subfield specialized on: Sequence analysis software. List of sequence alignment software
Bacteria also have subcellular localizations that can be separated when the cell is fractionated. The most common localizations referred to include the cytoplasm , the cytoplasmic membrane (also referred to as the inner membrane in Gram-negative bacteria), the cell wall (which is usually thicker in Gram-positive bacteria) and the extracellular ...
PSORT is a bioinformatics tool used for the prediction of protein localisation sites in cells. [1] [2] It receives the information of an amino acid sequence and its taxon of origin (e.g. Gram-negative bacteria) as inputs. Then it analyses the input sequence by applying the stored rules for various sequence features of known protein sorting signals.
PSORTdb is a database of protein subcellular localization (SCL) for bacteria and archaea.It is a member of the PSORT family of bioinformatics tools. [1] The database consists of two datasets, ePSORTdb and cPSORTdb, which contain information determined through experimental validation and computational prediction, respectively.