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A drug previously used to treat breast cancer is now being offered to high risk women as a preventative measure.. Scientists have found that the hormone therapy - called anastrozole - can p revent ...
Anastrozole, sold under the brand name Arimidex among others, is an antiestrogenic medication used in addition to other treatments for breast cancer. [6] [7] Specifically it is used for hormone receptor-positive breast cancer. [7] It has also been used to prevent breast cancer in those at high risk. [7] It is taken by mouth. [7]
Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...
Adverse effects of tamoxifen include hot flashes and an increase in the risk of developing endometrial cancer compared to women of similar age. [ 6 ] [ 4 ] Toremifene , a chlorinated tamoxifen derivative developed to avoid hepatic carcinomas , was associated with fewer DNA adducts in the liver than tamoxifen in preclinical studies .
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Antiandrogens are a class of drug which bind and inhibit the androgen receptor, blocking the growth- and survival-promoting effects of testosterone on certain prostate cancers. Flutamide and bicalutamide are antiandrogens which are frequently used in the treatment of prostate cancer, either as long-term monotherapy, or in the initial few weeks ...
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production .
Androgenic side effects are of concern, as some women taking danazol may experience unwanted hair growth , acne, irreversible deepening of the voice, [4] or adverse blood lipid profiles. [23] In addition, breast atrophy and decreased breast size may occur. [4] The drug may also cause hot flashes, elevation of liver enzymes, and mood changes.