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The Disposition index (DI) is a measure for the loop gain of the insulin-glucose feedback control system. It is defined as the product of insulin sensitivity times the amount of insulin secreted in response to blood glucose levels.
Race adjustment, also known as race-correction, [1] [2] is the calculating of a result which takes into account race. [1] It is commonly used in medical algorithms in several specialties, including cardiology , nephrology , urology , obstetrics , endocrinology , oncology and respiratory medicine . [ 1 ]
Continuous monitoring allows examination of how the blood glucose level reacts to insulin, exercise, food, and other factors. The additional data can be useful for setting correct insulin dosing ratios for food intake and correction of hyperglycemia. Monitoring during periods when blood glucose levels are not typically checked (e.g. overnight ...
IR is insulin resistance and %β is the β-cell function (more precisely, an index for glucose tolerance, i.e. a measure for the ability to counteract the glucose load). Insulin is given in μU/mL. [7] Glucose and insulin are both during fasting. [2] This model correlated well with estimates using the euglycemic clamp method (r = 0.88). [2]
A fudge factor is an ad hoc quantity or element introduced into a calculation, formula or model in order to make it fit observations or expectations. Also known as a correction coefficient , which is defined by
This leads the pancreas to produce more insulin, which helps lower blood sugar levels and promote weight loss. GLP-1 drugs for weight loss and type 2 diabetes include dulaglutide, liraglutide, and ...
Fieller, EC. (1940) "The biological standardisation of insulin". Journal of the Royal Statistical Society (Supplement). 1:1–54. JSTOR 2983630; Fieller, EC (1944). "A fundamental formula in the statistics of biological assay, and some applications". Quarterly Journal of Pharmacy and Pharmacology. 17: 117– 123.
This index correlates well with glucose clamp studies (r = 0.78), and is useful for measuring insulin sensitivity (IS), which is the inverse of insulin resistance (IR). It has the advantage of that it can be obtained from a fasting blood sample, and is the preferred method for certain types of clinical research.