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In addition to yielding anti-inflammatory eicosanoids, DGLA competes with AA for COX and lipoxygenase, inhibiting the production of AA's eicosanoids. Taken orally in a small study, DGLA produced antithrombotic effects. [5] Supplementing dietary GLA increases serum DGLA, as well as serum AA levels. [6]
However, it can inhibit the formation of pro-inflammatory leukotrienes from AA. [9] Although GLA is an n−6 fatty acid, a type of acid that is, in general, pro-inflammatory [citation needed], it has anti-inflammatory properties. (See discussion at Essential fatty acid interactions: The paradox of dietary GLA.)
Borage oil may contain the pyrrolizidine alkaloid amabiline, [6] [7] [8] which is hepatotoxic leading to a risk of liver damage. [1] Patients should use borage oil that is certified free of toxic unsaturated pyrrolizidine alkaloids (UPAs). [1] Consumption of 1-2 g of borage seed oil daily can result in an intake of toxic UPAs approaching 10 ug. [1]
1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...
Oenothera biennis, the common evening-primrose, [3] is a species of flowering plant in the family Onagraceae, native to eastern and central North America, from Newfoundland west to Alberta, southeast to Florida, and southwest to Texas, and widely naturalized elsewhere in temperate and subtropical regions. [4]
Make it 1,500 calories: Change P.M. snack to 1 cup blueberries and omit evening snack. Make it 2,000 calories: Add 1 cup low-fat plain kefir to lunch and add 1 medium banana to evening snack. Day 7
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