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Carvedilol is a nonselective beta blocker and alpha-1 blocker. [5] How it improves outcomes is not entirely clear but may involve dilation of blood vessels. [5] Carvedilol was patented in 1978 and approved for medical use in the United States in 1995. [5] [8] It is on the World Health Organization's List of Essential Medicines. [9]
Pipamperone acts as an antagonist of the 5-HT 2A, [7] 5-HT 2B, [8] 5-HT 2C [9] D 2, [7] D 3, [10] D 4, [7] [11] α 1-adrenergic, [10] and α 2-adrenergic receptors. [10] It shows much higher affinity for the 5-HT 2A and D 4 receptors over the D 2 receptor (15-fold in the case of the D 4 receptor, and even higher in the case of the 5-HT 2A receptor), [7] [10] [12] being regarded as "highly ...
Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker which is selective for the beta-1 receptor [7] and used for cardiovascular diseases, [7] including tachyarrhythmias, high blood pressure, angina, and heart failure.
Atenolol is available in the form of 25, 50, and 100 mg oral tablets. [21] [4] It is also available in the form of oral tablets containing a combination of 50 or 100 mg atenolol and 50 mg chlortalidone. [21] Atenolol was previously available in a 0.5 mg/mL solution for injection as well, but this formulation was discontinued. [21]
Captopril, sold under the brand name Capoten among others, is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure.
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine, specifically a cyclopyrrolone, used to treat difficulty sleeping.Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone.