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Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism. [1] The pH of the intracellular fluid and the extracellular fluid need to be ...
pH can be measured using indicators, which change color depending on the pH of the solution they are in. By comparing the color of a test solution to a standard color chart, the pH can be estimated to the nearest whole number. For more precise measurements, the color can be measured using a colorimeter or spectrophotometer.
Intracellular pH (pHi) is the measure of the acidity or basicity (i.e., pH) of intracellular fluid. The pH i plays a critical role in membrane transport and other intracellular processes. In an environment with the improper pH i, biological cells may have compromised function. [1][2] Therefore, pH i is closely regulated in order to ensure ...
Davenport diagram. In acid base physiology, the Davenport diagram is a graphical tool, developed by Horace W. Davenport, that allows a clinician or investigator to describe blood bicarbonate concentrations and blood pH following a respiratory and/or metabolic acid-base disturbance. The diagram depicts a three-dimensional surface describing all ...
The term acidemia describes the state of low blood pH, when arterial pH falls below 7.35 (except in the fetus – see below) while acidosis is used to describe the processes leading to these states. The use of acidosis for a low pH creates an ambiguity in its meaning. The difference is important where a patient has factors causing both acidosis ...
Acid–base imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of the normal range (7.35 to 7.45). In the fetus, the normal range differs based on which umbilical vessel is sampled (umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38). [1]
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. [1] Blood is composed of blood cells suspended in blood plasma.
The pH of gastric acid in humans is 1.5-2.0. This is a much lower pH level than that of most animals and very close to scavengers, which eat carrion. [12] This suggests that carrion feeding could have been more important in human evolution than previously thought. [12]