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  2. Barr body - Wikipedia

    en.wikipedia.org/wiki/Barr_body

    Barr bodies can be seen in neutrophils at the rim of the nucleus. In humans with more than one X chromosome, the number of Barr bodies visible at interphase is always one fewer than the total number of X chromosomes. For example, people with Klinefelter syndrome (47, XXY) have a single Barr body, and people with a 47, XXX karyotype have two ...

  3. Sex-chromosome dosage compensation - Wikipedia

    en.wikipedia.org/wiki/Sex-chromosome_dosage...

    Replicating the actual gene is impossible; thus organisms instead equalize the expression from each gene. For example, in humans, female (XX) cells randomly silence the transcription of one X chromosome, and transcribe all information from the other, expressed X chromosome. Thus, human females have the same number of expressed X-linked genes ...

  4. X-inactivation - Wikipedia

    en.wikipedia.org/wiki/X-inactivation

    The Xist gene is expressed at high levels on the Xi and is not expressed on the Xa. [39] Many other genes escape inactivation; some are expressed equally from the Xa and Xi, and others, while expressed from both chromosomes, are still predominantly expressed from the Xa. [40] [41] [42] Up to one quarter of genes on the human Xi are capable of ...

  5. X-chromosome reactivation - Wikipedia

    en.wikipedia.org/wiki/X-chromosome_reactivation

    X chromosome reactivation (XCR) is the process by which the inactive X chromosome (the Xi) is re-activated in the cells of eutherian female mammals. Therian female mammalian cells have two X chromosomes, while males have only one, requiring X-chromosome inactivation (XCI) for sex-chromosome dosage compensation.

  6. Nuclear sexing - Wikipedia

    en.wikipedia.org/wiki/Nuclear_sexing

    Nuclear sexing can be done by identifying Barr body, a drumstick like appendage located in the rim of the nucleus in somatic cells. Barr body is the inactive X chromosome which lies condensed in the nucleus of somatic cells. A typical human (or other XY-based organism) female has only one Barr body per somatic cell, while a typical human male ...

  7. Lists of human genes - Wikipedia

    en.wikipedia.org/wiki/Lists_of_human_genes

    •List of human protein-coding genes page 4 covers genes SLC17A8–ZZZ3 NB: Each list page contains 5000 human protein-coding genes, sorted alphanumerically by the HGNC-approved gene symbol. Follow the Python code link for information about updates to the list of genes on these pages.

  8. List of genetic disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_genetic_disorders

    The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child.

  9. X chromosome - Wikipedia

    en.wikipedia.org/wiki/X_chromosome

    The Barr body is indicated by the arrow, it identifies the inactive X (Xi). The X chromosome in humans spans more than 153 million base pairs (the building material of DNA ). It represents about 800 protein-coding genes compared to the Y chromosome containing about 107 protein-coding genes (42 exclusive protein-coding genes), [ 8 ] out of ...