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U.S. Route 66 (US 66, Route 66) is a former east–west United States Numbered Highway, running from Santa Monica, California to Chicago, Illinois.In Missouri, the highway ran from downtown St. Louis at the Mississippi River to the Kansas state line west of Joplin.
Near the AR/MO/OK tripoint. North of Joplin, Route 43 is a relatively straight highway. It intersects U.S. Route 160 in Barton County west of Lamar. A few miles south of there it intersects Route 126. Just north of Joplin, it intersects Route 96. In Joplin, the highway is known as Main Street and passes through the old historic downtown area.
Joplin is the main hub of the three-county Joplin-Miami, Missouri-Oklahoma Metro area, which is home to 210,077 people; this makes the city the fifth largest metropolitan area in Missouri. In May 2011, a violent EF5 tornado killed more than 150 people and destroyed one-third of the city.
Route 249 begins at an interchange with I-44, I-49, and US 71 east of Joplin in Jasper County, where the road continues south as I-49/US 71.The route heads north as a four-lane freeway through agricultural areas with some nearby development, coming to an interchange with Route 66/I-44 Bus. west of Duenweg.
Interstate 44 (I-44) in the US state of Missouri runs northeast from the Oklahoma state line near Joplin to I-70 in Downtown St. Louis. It runs for about 293 miles (472 km) in the state, and is the longest Interstate Highway in the state.
I-49 and US 71 pass through many smaller communities before reaching Joplin. In Joplin, I-49 and US 71 interchanges with Interstate 44 and begin a short concurrency from I-44 exits 11 through 18. A few miles east of Joplin, I-49 and US 71 leave I-44 and heads north and enters Carthage. Due to the freeway being built, old sections of the highway ...
Cumberland Church Road in Overton: 1922: current Route 99: 14.9: 24.0 Route 30 in St. Louis: US 66 / US 67 / US 40 Byp. in Bellefontaine Neighbors: 1929 — Former highway bypassing Downtown St. Louis [1] Route 99: 18.3: 29.5 US 160 east of West Plains: US 60 in Birch Tree — — Route 100: 121.144: 194.962 US 50 in Linn: 3rd Street in St. Louis
The route crosses into Joplin and intersects the southern terminus of Route P. Route 66 continues as a four-lane undivided road through commercial areas, running to the north of a Missouri and Northern Arkansas Railroad line for a time. The road passes a mix of homes and businesses before it heads into downtown Joplin and intersects I-44 Bus.