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Short QT syndrome (SQT) is a very rare genetic disease of the electrical system of the heart, and is associated with an increased risk of abnormal heart rhythms and sudden cardiac death. [1] The syndrome gets its name from a characteristic feature seen on an electrocardiogram (ECG) – a shortening of the QT interval .
In 20% of cases, no cause of death can be found, even after extensive examination. [13] Sudden arrhythmic death syndrome in alcohol abuse is a significant cause of death among heavy drinkers, characterized by older age and severe liver damage, highlighting the need for family screening for heritable channelopathies. [4]
Short QT syndrome; Short rib – polydactyly syndrome; ... Sudden infant death syndrome; Sudden wealth syndrome; Sugarman syndrome; Sulfonamide hypersensitivity syndrome;
In 2016, the WHO recorded 56.7 million deaths [3] with the leading cause of death as cardiovascular disease causing more than 17 million deaths (about 31% of the total) as shown in the chart to the side. In 2021, there were approx. 68 million deaths worldwide, as per WHO report.
This could help elucidate the cause of death in the patient. Other physical signs or symptoms can help determine the potential cause of the cardiac arrest. [30] Below is a chart of the clinical findings and signs/symptoms a person may have and potential causes associated with them.
Timothy syndrome, which may or may not occur with syndactyly; Short QT syndrome or Brugada syndrome; Long QT syndrome or other arrhythmia without additional symptoms. [2] CACNA1C-related disorders are inherited in an autosomal dominant manner. [2]
Abnormalities in this system occur in relatively rare genetic diseases such as Long QT syndrome, Brugada syndrome, and Catecholaminergic polymorphic ventricular tachycardia, all associated with sudden death. Consequently, autopsy-negative sudden cardiac deaths (no physical abnormalities identified) may comprise a larger part of the ...
Torsades occurs as both an inherited (linked to at least 17 genes) [6] and as an acquired form caused most often by drugs and/or electrolyte disorders that cause excessive lengthening of the QT interval. [7] Common causes for torsades de pointes include drug-induced QT prolongation and less often diarrhea, low serum magnesium, and low serum ...