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Several drugs and agrochemicals contain only one fluorine center or one trifluoromethyl group. Unlike other greenhouse gases in the Paris Agreement, hydrofluorocarbons have other international negotiations. [7] In September 2016, the so-called New York Declaration urged a global reduction in the use of HFCs. [8]
Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7]
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
Nearly a week after Lupin Pharmaceuticals announced a voluntary recall of two types of blood pressure medications, the company continues to see its stock price slide (though the hit could have ...
Fluorines also find their uses in common mineralocorticoids, a class of drugs that increase the blood pressure. Adding a fluorine increases both its medical power and anti-inflammatory effects. [16] Fluorine-containing fludrocortisone is one of the most common of these drugs. [17]
Perfluoroalkanes are very stable because of the strength of the carbon–fluorine bond, one of the strongest in organic chemistry. [4] Its strength is a result of the electronegativity of fluorine imparting partial ionic character through partial charges on the carbon and fluorine atoms, which shorten and strengthen the bond (compared to carbon-hydrogen bonds) through favorable covalent ...
Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors.It is used for essential (primary) hypertension. [2] While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.
Abiomed's so-called recall of some models of its Impella Left Sided Blood Pumps, used in some high-risk heart procedures to provide short-term support, was because of the possibility they could ...