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It is prepared by disulfonation of benzoic acid followed by hydrolysis of the disulfonate. [3] It is a metabolite of alkylresorcinols, first identified in human urine [4] and can be quantified in urine [5] and plasma, [6] and may be an alternative, equivalent biomarker of whole grain wheat intake. [7]
Dihydroxybenzoic acids (DHBA) are a type of phenolic acids. There are six main compounds, having all the same molecular formula C 7 H 6 O 4. Those are: 2,3-Dihydroxybenzoic acid (2-Pyrocatechuic acid or hypogallic acid) 2,4-Dihydroxybenzoic acid (β-Resorcylic acid) 2,5-Dihydroxybenzoic acid (Gentisic acid) 2,6-Dihydroxybenzoic acid (γ ...
Gentisic acid is produced by carboxylation of hydroquinone. [6] C 6 H 4 (OH) 2 + CO 2 → C 6 H 3 (CO 2 H)(OH) 2. This conversion is an example of a Kolbe–Schmitt reaction. Alternatively the compound can be synthesized from salicylic acid via Elbs persulfate oxidation. [7] [8]
UV visible spectrum of protocatechuic acid. Protocatechuic acid (PCA) is a dihydroxybenzoic acid, a type of phenolic acid. It is a major metabolite of antioxidant polyphenols found in green tea. It has mixed effects on normal and cancer cells in in vitro and in vivo studies. [4] It is produced commercially from vanillin. [5]
2,3-Dihydroxybenzoic acid is a natural phenol found in Phyllanthus acidus [2] and in the aquatic fern Salvinia molesta. [3] It is also abundant in the fruits of Flacourtia inermis. It is a dihydroxybenzoic acid, a type of organic compound. The colorless solid occurs naturally, being formed via the shikimate pathway.
2,4-Dihydroxybenzoic acid (β-resorcylic acid) is a dihydroxybenzoic acid. As a resorcylic acid, it is one of the three isomeric crystalline acids that are both carboxyl derivatives of resorcinol and dihydroxy derivatives of benzoic acid. [4] Synthesis from resorcinol is via the Kolbe-Schmitt reaction. [5]
This category has the following 3 subcategories, out of 3 total. D. Dihydroxybenzoic acids (20 P) M. Monohydroxybenzoic acids (1 C, 6 P) T. Trihydroxybenzoic acids (14 P)
2,3-diDHB dehydrogenase catalyzes the NAD +-dependent oxidation of 2,3-dihydro-2,3-dihydroxybenzoate to produce an aromatic compound 2,3-dihydroxybenzoic acid (2,3-DHB or simply DHB). [4] In times of iron deficiency, iron uptake is controlled by three genes: ent , fep , and fes for synthesis, export, and uptake of ferric Enterobactin and its ...