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  2. Cancer cell - Wikipedia

    en.wikipedia.org/wiki/Cancer_cell

    Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells. Cell division is a normal process used by the body for growth and repair. A parent cell divides to form two daughter cells, and these daughter cells are used to build new tissue or to replace cells that have died because of ...

  3. The Hallmarks of Cancer - Wikipedia

    en.wikipedia.org/wiki/The_Hallmarks_of_Cancer

    The ability to invade surrounding tissue and metastasise is a hallmark of cancer.. The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities.

  4. Warburg hypothesis - Wikipedia

    en.wikipedia.org/wiki/Warburg_hypothesis

    [4] [5] The metabolic difference observed by Warburg adapts cancer cells to the hypoxic (oxygen-deficient) conditions inside solid tumors, and results largely from the same mutations in oncogenes and tumor suppressor genes that cause the other abnormal characteristics of cancer cells. [6]

  5. HeLa - Wikipedia

    en.wikipedia.org/wiki/HeLa

    HeLa cells are rapidly dividing cancer cells, and the number of chromosomes varies during cancer formation and cell culture. The current estimate (excluding very tiny fragments) is a "hypertriploid chromosome number (3n+)", which means 76 to 80 total chromosomes (rather than the normal diploid number of 46) with 22–25 clonally abnormal ...

  6. Cancer - Wikipedia

    en.wikipedia.org/wiki/Cancer

    Cancers are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat. Cancer is fundamentally a disease of tissue growth regulation. For a normal cell to transform into a cancer cell, the genes that regulate cell growth and differentiation must be altered. [96] The affected genes are divided into two broad categories.

  7. Carcinogenesis - Wikipedia

    en.wikipedia.org/wiki/Carcinogenesis

    The cancer stem cell hypothesis proposes that the different kinds of cells in a heterogeneous tumor arise from a single cell, termed Cancer Stem Cell. Cancer stem cells may arise from transformation of adult stem cells or differentiated cells within a body. These cells persist as a subcomponent of the tumor and retain key stem cell properties.