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Assessment of kidney function occurs in different ways, ... After age 40, GFR decreases progressively with age, by 0.4–1.2 mL/min per year. [citation needed]
Risk factors for kidney disease include diabetes, high blood pressure, family history, older age, ethnic group and smoking. For most patients, a GFR over 60 mL/min/1.73 m 2 is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention.
The kidney is a very complex organ and mathematical modelling has been used to better understand kidney function at several scales, including fluid uptake and secretion. [ 35 ] [ 36 ] Clinical significance
The National Kidney Foundation notes that kidney disease can happen at any age but is more common in people over the age of 60. ... "Ask for your kidney function to be tested," Atkinson says ...
Chronic kidney disease (CKD) is a type of long-term kidney disease, in which either there is a gradual loss of kidney function which occurs over a period of months to years, or an abnormal kidney structure (with normal function).
Acute kidney injuries can be present on top of chronic kidney disease, a condition called acute-on-chronic kidney failure (AoCRF). The acute part of AoCRF may be reversible, and the goal of treatment, as with AKI, is to return the person to baseline kidney function, typically measured by serum creatinine.
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