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Phenazopyridine is a medication which, when excreted by the kidneys into the urine, has a local analgesic effect on the urinary tract. It is often used to help with the pain , irritation , or urgency caused by urinary tract infections , surgery , or injury to the urinary tract.
Swallowing a handful of pills is a daily ritual for many people, from young adults coping with anxiety to older adults managing chronic conditions. Overall, 13% of people in the U.S. take five or ...
Pfizer announced on Dec. 1 that it was discontinuing phase 3 clinical trials of the twice-daily version due to high rates of adverse side effects. While these were mostly mild, a large percentage ...
Phenmetrazine, sold under the brand name Preludin among others, is a stimulant drug first synthesized in 1952 and originally used as an appetite suppressant, but withdrawn from the market in the 1980s due to widespread misuse.
It shares many of the side effects of other opioids like constipation, nausea, itching, drowsiness and respiratory depression, but unlike most other opioids it fairly frequently causes hallucinations, nightmares and delusions. It is also, unlike most other opioids, subject to a ceiling effect, which is when at a certain dose (which differs from ...
Pfizer characterized the side effects in the twice-daily version study as mild, but the rates were high with more than half of those on the drug dropping out compared with discontinuation rate of ...