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Leiomyoma enucleated from a uterus. External surface on left; cut surface on right. Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei Immunohistochemistry for β-catenin in uterine leiomyoma, which is negative as there is only staining of cytoplasm ...
Abnormal uterine bleeding in the reproductive years comprises a complex set of disorders that include abnormalities in endocrine, endometrial and hemostatic function and a number of structural anomalies that include polyps, adenomyosis and leiomyomas or fibroids.
An enucleated uterine leiomyoma – external surface on left, cut surface on right. Fibroids are a type of uterine leiomyoma. Fibroids grossly appear as round, well circumscribed (but not encapsulated), solid nodules that are white or tan, and show whorled appearance on histological section.
Whether or not angiomyomas are a type of leiomyoma or a separate entity is disputed as of 2014. [3] Myomas are benign tumors of the uterus that can affect the fertility of a woman depending mainly on three factors: Size (cut off value 4-5 cm) Number; Location (they can be intramural, subserous or submucous).
In FAP, adenomatous polyps are present in the colon. The polyps progress into colon cancer unless removed. [17] The APC gene is a tumor suppressor. Its protein product is involved in many cellular processes. Inactivation of the APC gene leads to the buildup of a protein called β-catenin.
Cutaneous leiomyoma, also known as leiomyoma cutis, [1] or cutaneous leiomyomata, [2] is a benign skin tumor made of smooth muscle cells. [3] There are three different types of cutaneous leiomyomas, genital leiomyomas, angioleiomyomas, and piloleiomyomas. Cutaneous leiomyomas can occur sporadically or as a part of a genetic condition.
A polyp is an abnormal growth of tissue projecting from a mucous membrane. If it is attached to the surface by a narrow elongated stalk, it is said to be pedunculated; if it is attached without a stalk, it is said to be sessile. Polyps are commonly found in the colon, stomach, nose, ear, sinus(es), urinary bladder, and uterus.
The localized form is a single mass, typically in the fundus, that protrudes into the lumen of the gallbladder in the form of a polyp. [ 5 ] [ 6 ] The segmental form is characterized by its annular (ring-shaped) distribution of adenomyomatosis in the body of the gallbladder, often giving it an hourglass-like appearance.