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Since there are a ton of nerve endings in such a small area, stimulating it can lead to some pretty memorable orgasms. “The frenulum is a kind of pleasure center for the penis, alongside its ...
A free nerve ending (FNE) or bare nerve ending, is an unspecialized, afferent nerve fiber sending its signal to a sensory neuron. Afferent in this case means bringing information from the body's periphery toward the brain. They function as cutaneous nociceptors and are essentially used by vertebrates to detect noxious stimuli that often result ...
The activation of the sympathetic nervous system leads to the release of norepinephrine from nerve endings acting on the heart, blood vessels, respiratory centers, and other sites. The ensuing physiological changes constitute a major part of the acute stress response.
Meckel nerve endings are most numerous beneath the ridges of the fingertips which make up fingerprints, and less so in the palms and forearm. [citation needed] They can be found at a depth of 900 µm in human fingertips. [4] In hairy skin, Merkel nerve endings are clustered into specialized epithelial structures called "touch domes" or "hair ...
By comparison, the palm of one’s hand has 17,000 nerve endings — in a much, much larger area. Yet this study on the clitoris provides more than just a fun fact — it also can have major ...
Likewise, camphor is easily absorbed into the skin and stimulates nerve endings sensitive to cold, which causes a cooling sensation, relieving pain. These biological compounds provide a comforting ...