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A motor neuron (or motoneuron or efferent neuron [1]) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. [2]
Photomicrograph of Nissl bodies (two are indicated by arrows) in the cytoplasm of motor neurons in the anterior horn of the spinal cord; cresyl violet stain (purple) along with a luxol fast blue stain for myelin. Scale bar = 30 microns (0.03mm). Drawing of a motor neuron from the ventral horn of the medulla spinals of a rabbit.
Each area is made up of many segments. Motor and sensory nerve fibers to and from every area of the body are found in the spinal nerve. A dermatome is innervated by each segment of the spinal cord. The spinal cord is organized into segments, each corresponding to specific regions of the body: 8 cervical (neck) 12 thoracic (chest) 5 lumbar ...
Central pattern generators are groups of neurons in the spinal cord that are responsible for generating stereotyped movement. It has been shown that in cats, rhythmic activation patterns are still observed following removal of sensory afferents and removal of the brain., [1] indicating that there is neural pattern generation in the spinal cord independent of descending signals from the brain ...
These neurons are the largest in the central nervous system, sometimes reaching 100 μm in diameter. [ 1 ] [ 2 ] Betz cells are upper motor neurons that send their axons down to the spinal cord via the corticospinal tract, where in humans they synapse directly with anterior horn cells , which in turn synapse directly with their target muscles .
A simple view, that is almost certainly too limited and that dates back to the earliest work on the motor cortex, is that neurons in the motor cortex control movement by a feed-forward direct pathway. In that view, a neuron in the motor cortex sends an axon or projection to the spinal cord and forms a synapse on a motor neuron. The motor neuron ...
Corticospinal neurons synapse directly onto alpha motor neurons for direct muscle control. Betz cells are very large cells that are very visible under a microscope, and while they account for only about 5% of cells projecting to the spinal cord, they are often considered most crucial for communication of motor signals. [2]
Spinal cord segment. The central pattern generators responsible for locomotion in vertebrates reside as half-center modules in the cervical and lumbar region of the spinal cord. Each CPG generates a basic motor output pattern that is responsible for the rhythmic contractions of flexor-extensor muscles that correspond to the forelimbs and ...