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Lemierre's syndrome is infectious thrombophlebitis of the internal jugular vein. [2] It most often develops as a complication of a bacterial sore throat infection in young, otherwise healthy adults. The thrombophlebitis is a serious condition and may lead to further systemic complications such as bacteria in the blood or septic emboli .
This bacterium has been found to be associated with the foot disease thrush in horses. Thrush is a common infection that occurs on the hoof of a horse, specifically in the region of the frog. F. necrophorum occurs naturally in the animal's environment, especially in wet, muddy, or unsanitary conditions, such as an unclean stall.
Strains of Fusobacterium can cause several human diseases and infections, including periodontal diseases, Lemierre's syndrome, [8] oral, head, and neck infections, as well as colorectal cancer and topical skin ulcers. [9] It has been tied [clarification needed] to HIV infection and suboptimal immune recovery. [10]
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Infectious and Parasitic Diseases II 140–239: Neoplasms III 240–279: Endocrine, Nutritional and Metabolic Diseases, and Immunity Disorders IV 280–289: Diseases of the Blood and Blood-forming Organs V 290–319: Mental Disorders VI 320–389: Diseases of the Nervous System and Sense Organs VII 390–459: Diseases of the Circulatory System ...
Fusobacterium nucleatum is a Gram-negative, anaerobic bacterium, commensal to the human oral cavity, that plays a role in periodontal disease. This organism is commonly recovered from different monocultured microbial and mixed infections in humans and animals.
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A young man develops severe headaches, loss of concentration, vomiting, hydrocephalus and falls into a coma from a brain infection caused by Taenia solium; a university student gets a sore throat, fevers, loss of balance, and organ failure from Lemierre's syndrome, caused by Fusobacterium necrophorum; a young woman suffers from emotional ...