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The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [13] by Abraham Wald in the context of sequential tests of statistical hypotheses. [14]
In statistics, Box–Behnken designs are experimental designs for response surface methodology, devised by George E. P. Box and Donald Behnken in 1960, to achieve the following goals: Each factor, or independent variable, is placed at one of three equally spaced values, usually coded as −1, 0, +1.
The Design of Experiments is a 1935 book by the English statistician Ronald Fisher about the design of experiments and is considered a foundational work in experimental design. [ 1 ] [ 2 ] [ 3 ] Among other contributions, the book introduced the concept of the null hypothesis in the context of the lady tasting tea experiment. [ 4 ]
Blocking: A schedule for conducting treatment combinations in an experimental study such that any effects on the experimental results due to a known change in raw materials, operators, machines, etc., become concentrated in the levels of the blocking variable. Note: the reason for blocking is to isolate a systematic effect and prevent it from ...
In the statistical theory of the design of experiments, blocking is the arranging of experimental units in groups (blocks) that are similar to one another. Typically, a blocking factor is a source of variability that is not of primary interest to the experimenter. [3] [4] No blocking (left) vs blocking (right) experimental design
Plackett–Burman designs are experimental designs presented in 1946 by Robin L. Plackett and J. P. Burman while working in the British Ministry of Supply. [1] Their goal was to find experimental designs for investigating the dependence of some measured quantity on a number of independent variables (factors), each taking L levels, in such a way as to minimize the variance of the estimates of ...
Bayesian experimental design provides a general probability-theoretical framework from which other theories on experimental design can be derived. It is based on Bayesian inference to interpret the observations/data acquired during the experiment. This allows accounting for both any prior knowledge on the parameters to be determined as well as ...
Designed experiments with full factorial design (left), response surface with second-degree polynomial (right) In statistics, a factorial experiment (also known as full factorial experiment) investigates how multiple factors influence a specific outcome, called the response variable.