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In July 2013, the State President, Mr Jacob Zuma, announced the name of the new university as the University of Mpumalanga as well as the names of the members of the Interim Council to oversee its formal establishment. The University of Mpumalanga, a comprehensive university, was formally and legally promulgated through the publication of ...
[9] [10] These separate conformational forms display different enzymatic activities, with the UMP synthase monomer displaying low decarboxylase activity, and only the 5.6 S dimer exhibiting full decarboxylase activity. [11] It is believed that the two separate catalytic sites fused into a single protein to stabilize its monomeric form.
Uridine monophosphate (UMP), also known as 5′-uridylic acid (conjugate base uridylate), is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside uridine. UMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase uracil; hence, it is a ribonucleotide monophosphate.
In yeast and bacteria, OMP decarboxylase is a single-function enzyme.However, in mammals, OMP decarboxylase is part of a single protein with two catalytic activities.This bifunctional enzyme is named UMP synthase and it also catalyzes the preceding reaction in pyrimidine nucleotide biosynthesis, the transfer of ribose 5-phosphate from 5-phosphoribosyl-1-pyrophosphate to orotate to form OMP.
In enzymology, an UMP kinase (EC 2.7.4.22) is an enzyme that catalyzes the chemical reaction ATP + UMP ⇌ {\displaystyle \rightleftharpoons } ADP + UDP Thus, the two substrates of this enzyme are ATP and UMP , whereas its two products are ADP and UDP .
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Adobe expects foreign exchange volatility and the company's shift towards subscriptions to cut into its fiscal 2025 revenue by about $200 million. The company is making significant investments in ...