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The partial pressure of oxygen (pO 2) in the pulmonary alveoli is required to calculate both the alveolar-arterial gradient of oxygen and the amount of right-to-left cardiac shunt, which are both clinically useful quantities. However, it is not practical to take a sample of gas from the alveoli in order to directly measure the partial pressure ...
The alveolar oxygen partial pressure is lower than the atmospheric O 2 partial pressure for two reasons.. Firstly, as the air enters the lungs, it is humidified by the upper airway and thus the partial pressure of water vapour (47 mmHg) reduces the oxygen partial pressure to about 150 mmHg.
Arterial blood oxygen tension (normal) P a O 2 – Partial pressure of oxygen at sea level (160 mmHg (21.3 kPa) in the atmosphere, 21% of the standard atmospheric pressure of 760 mmHg (101 kPa)) in arterial blood is between 75 and 100 mmHg (10.0 and 13.3 kPa).
2, [1] or A–a gradient), is a measure of the difference between the alveolar concentration (A) of oxygen and the arterial (a) concentration of oxygen. It is a useful parameter for narrowing the differential diagnosis of hypoxemia. [2] The A–a gradient helps to assess the integrity of the alveolar capillary unit.
This is calculated by dividing the PaO2 by the FiO2. Example: patient who is receiving an FiO2 of .5 (i.e., 50%) with a measured PaO2 of 60 mmHg has a PaO 2 / FiO 2 ratio of 120. In healthy lungs, the Horowitz index depends on age and usually falls between 350 and 450.
Pulse oximetry is a method used to estimate the percentage of oxygen bound to hemoglobin in the blood. [10] This approximation to SaO 2 is designated SpO 2 (peripheral oxygen saturation). The pulse oximeter is a small device that clips to the body (typically a finger, an earlobe or an infant's foot) and displays its reading, or transfers it to ...
An arterial blood gas (ABG) test, or arterial blood gas analysis (ABGA) measures the amounts of arterial gases, such as oxygen and carbon dioxide.An ABG test requires that a small volume of blood be drawn from the radial artery with a syringe and a thin needle, [1] but sometimes the femoral artery in the groin or another site is used.
The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body. A lower oxygenation index is better - this can be inferred by the equation itself. As the oxygenation of a person improves, they will be able to achieve a higher PaO2 at a lower FiO2.