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Doxycycline is highly lipophilic, so it can easily enter cells, meaning the drug is easily absorbed after oral administration and has a large volume of distribution. It can also be re-absorbed in the renal tubules and gastrointestinal tract due to its high lipophilicity, giving it a long elimination half-life .
A hyclate (Latin: hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate [1] [2] (·HCl· 1 / 2 EtOH· 1 / 2 H 2 O), e.g. doxycycline hyclate. [ 3 ] [ 4 ] References
Generic name Brand names Common uses [4] Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All ...
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
It is used as a precursor in the industrial synthesis of doxycycline hyclate. [citation needed] It has been found to act as an agonist of the human pregnane X receptor ligand-binding domain and to induce CYP3A4 expression in vitro. [1]
An archaic English term for prostitute; Doxy (song), a jazz standard by Sonny Rollins; Doxy, a magical creature in the fictional Harry Potter universe; Doxy.me a simple and free telemedicine software for healthcare professionals; Doxycycline, an antibiotic drug; Doxylamine, an antihistamine drug; An abbreviation for Doxygen, a software package
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Doxycycline. Doxycycline is a semi-synthetic tetracycline that has been studied for dental and medical applications. Its effects on diseases like periodontitis and cancer has been investigated. [2] Doxycycline is nearly completely absorbed with a bioavailability about 95% in average and a 20% reduction with co-administration of food.